反应详情

The triazole from Procedure 1 (41.2 g., 0.31 mole) was dissolved in a solution of 12.19 g. (0.31 mole) of NaOH in 230 ml. of water at 80°. The solution was then chilled at 5° and left overnight. The resulting precipitate was collected on a filter and dried under reduced pressure, to afford 36.0 g. (75%) of light yellow salt, m.p. 320°. Concentration of the mother liquors afforded an additional 8.3 g. (17%) of salt. The triazole of Procedure 2 was converted to the sodium salt in the same fashion.

1. customat 80°
2. temperatureThe solution was then chilled at 5°
3. customThe resulting precipitate was collected on
4. filtrationa filter
5. customdried under reduced pressure
6. customto afford 36.0 g
7. customConcentration of the mother liquors afforded an additional 8.3 g