HuagongsheHuagongshe Chemistry Print Report · For research reference only
10-[(3RS,4RS)-7-hydroxy-3-(4-hydroxyphenyl)-3-propylthiochroman-4-yl]-2-(4,4,5,5,5-pentafluoropentyl)decanoic acid → 11-[(3Rs,4rs)-7-hydroxy-3-(4-hydroxyphenyl)-3-propylthiochroman-4-yl]-2-(4,4,5,5,5,-pentafluoropentyl)undecanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 10-[(3RS,4RS)-7-hydroxy-3-(4-hydroxyphenyl)-3-propylthiochroman-4-yl]-2-(4,4,5,5,5-pentafluoropentyl)decanoic acid | HCID 10211406 | — |
| Reactant | Ethyl 2-(4,4,5,5,5-pentafluoropentyl)-9-decenoate | HCID 12043786 | — |
| Product | 11-[(3Rs,4rs)-7-hydroxy-3-(4-hydroxyphenyl)-3-propylthiochroman-4-yl]-2-(4,4,5,5,5,-pentafluoropentyl)undecanoic acid | HCID 10282995 | — |
Reaction Steps
Starting with the allyl compound prepared in Example 29 and ethyl 2-(4,4,5,5,5,-pentafluoropentyl)-9-decenoate prepared separately, the same procedure as shown in Example 13 was repeated to give 11-[(3RS,4RS)-7-hydroxy-3-(4-hydroxyphenyl)-3-propylthiochroman-4-yl]-2-(4,4,5,5,5,-pentafluoropentyl)undecanoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06552068B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-3e7ff9321b834cf687237312c1e5f3f0 |
| Source note | uspto-grants-2003_04 |