Water → 1,3-Benzenedicarboxylic acid, 2-hydroxy- (9CI)

HRID 1268227Notes

Reaction equation

HRID 1268227 reaction equation
C[O:2][C:3]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6].O>I>[OH:2][C:3]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6]

Participants

4

Reactant 2

HCID 962WaterHCID 45588112-Methoxyisophthalic acid

Product 1

HCID 118121,3-Benzenedicarboxylic acid, 2-hydroxy- (9CI)Yield 96.9%

Reagents, catalysts & solvents 1

HCID 24841Hydrogen iodideSolvent

Procedure

A solution of 2-methoxyisophthalic acid (1.0 g) in 55% hydriodic acid (10 ml) was heated at 80° C. for 1 hour. The reaction mixture was poured into iced water and the precipitate was collected by filtration to give the desired compound (0.9 g, yield 95%) as a pale yellow solid.

Workup

  1. filtrationthe precipitate was collected by filtration

Sources & evidence

ORD record
ord-8ee74bf8a9f14c3889bdec5d716637ae
Source dataset
uspto-grants-2003_04
Patent number
US06555556B1

Reaction notes

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