Diisobutylaluminum hydride → HCID 22557552, compound

HRID 1268278Notes

Reaction equation

HRID 1268278 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5](/[C:8](/[CH3:16])=[C:9](\[CH3:15])/[C:10](OCC)=[O:11])=[CH:4][CH:3]=1.CC(C[AlH]CC(C)C)C>>[Br:1][C:2]1[CH:3]=[CH:4][C:5](/[C:8](/[CH3:16])=[C:9](\[CH3:15])/[CH2:10][OH:11])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 14487Diisobutylaluminum hydrideHCID 86589951HCID 86589951, compound

Product 1

HCID 22557552HCID 22557552, compound

Procedure

(E)-Ethyl 3-(4-bromophenyl)-2-methyl-but-2-enoate (2.83 g, 9.99 mmol) was reduced with DIBAL-H by a procedure analogous to that described in example 52b to give (E)-3-(4-bromophenyl)-2-methyl-but-2-en-1-ol as a colourless oil; 1.82 g (75%).

Sources & evidence

ORD record
ord-53f45061cb5949e8b479661badb22714
Source dataset
uspto-grants-2003_04
Patent number
US06555577B1

Reaction notes

Loading…