Diisobutylaluminum hydride → HCID 22557697, compound

HRID 1268315Notes

Reaction equation

CC(C[AlH]CC(C)C)C.[CH:10]([C:13]1[CH:18]=[CH:17][C:16]([C:19]2[CH:24]=[CH:23][C:22](/[C:25](/[CH3:32])=[CH:26]/[C:27](OCC)=[O:28])=[CH:21][CH:20]=2)=[CH:15][CH:14]=1)([CH3:12])[CH3:11]>>[CH:10]([C:13]1[CH:18]=[CH:17][C:16]([C:19]2[CH:20]=[CH:21][C:22](/[C:25](/[CH3:32])=[CH:26]/[CH2:27][OH:28])=[CH:23][CH:24]=2)=[CH:15][CH:14]=1)([CH3:12])[CH3:11]

Participants

Reactant 2

HCID 14487Diisobutylaluminum hydride

HCID 22557676HCID 22557676, compound

Product 1

HCID 22557697HCID 22557697, compound

Procedure

The colourless solid (E)-3-(4′-isopropyl-biphenyl-4-yl)-but-2-en-1-ol was prepared by DIBAL-H reduction of (E)-ethyl 3-(4′-isopropyl-biphenyl-4-yl)-but-2-enoate by a procedure analogous to that described in example 50b.

Sources & evidence

ORD record: ord-85a4c0c9bed7449aa8282c66b53200ed
Source dataset: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06555577B1

Reaction notes

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