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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1268402Generated: October 30, 2026

Ethanol → Ethyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoate

https://huagongshe.com/reaction/1268402

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant2-(4-Cyclopropanecarbonyl-phenyl)-2-methylpropionamideHCID 23499851—
ProductEthyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoateHCID 9813859—

Reaction Steps

Dissolve 2-(4-cyclopropanecarbonyl-phenyl)-2-methyl-propionamide (100 mg) in ethanol and bubble in hydrochloride gas for 5 minutes while stirring. Reflux for 10 hours, distill off the ethanol and extract into ethyl acetate. Evaporate the solvent in vacuo to give the title compound as an oil (50 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06555689B2
Source datasetuspto-grants-2003_04
ORD IDord-89c6508aa28a4737b02b6b676299f8fb
Source noteuspto-grants-2003_04