HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 1-Acetyl-4-piperidineacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (1-Acetylpiperidin-4-yl)acetic acid | HCID 10442408 | — |
| Product | 1-Acetyl-4-piperidineacetyl chloride | HCID 20288065 | 95% |
Reaction Steps
To 240 parts of thionyl chloride are added portionwise 25 parts of 1-acetyl-4-piperidineacetic acid and the whole is stirred overnight at room temperature. The reaction mixture is evaporated, yielding 26.5 parts (95%) of 1-acetyl-4-piperidineacetyl chloride as an oily residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04254127 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-6d0ab50928a64ba0a9220c1c4b1ab58e |
| Source note | uspto-grants-1981_03 |