HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 907659, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 4-{[(2S)-butan-2-yl]oxy}benzoate | HCID 18446984 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 907659 | HCID 907659 | 86% |
Reaction Steps
A solution of 1.0 g (4.8 mmol) of methyl 4-(2-(S)-butoxy)benzoate in 15 mL of MeOH was treated with 1 mL of 5.0 N NaOH at rt for 1 h. The solution was concentrated, acidified with 6 mL of 2 N HCl, extracted with EtOAc, dried over MgSO4 and concentrated to afford 800 mg (86%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07199142B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-6d2197054abd40418d2a49822f2abbb3 |
| Source note | uspto-grants-2007_04 |