HRID1269200

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID74637

2,2-Diphenylacetyl chloride

C14H11ClO

结构：CCCC(=O)Nc1ccc(OC)c(C2CCN(CCCN)CC2)c1

HCID21957241

未命名化合物

PRODUCTS

生成物

结构：CCCC(=O)Nc1ccc(OC)c(C2CCN(CCCNC(=O)C(c3ccccc3)c3ccccc3)CC2)c1

HCID21957155

未命名化合物

PROCEDURE

实验过程

Example 22 was prepared from diphenyl acetyl chloride and N-{3-[1-(3-aminopropyl)-4-piperidinyl]-4-methoxyphenyl}butanamide according to the procedures described in Scheme 8: ESMS m/e: 528.4 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b5cc0f0957ac4c6a9ae4949296be5059
来源数据集: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07199135B2
来源说明: uspto-grants-2007_04

反应 SMILES

[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:17][CH2:18][CH2:19][CH2:20][N:21]1[CH2:26][CH2:25][CH:24]([C:27]2[CH:28]=[C:29]([NH:35][C:36](=[O:40])[CH2:37][CH2:38][CH3:39])[CH:30]=[CH:31][C:32]=2[O:33][CH3:34])[CH2:23][CH2:22]1>>[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8]([NH:17][CH2:18][CH2:19][CH2:20][N:21]2[CH2:26][CH2:25][CH:24]([C:27]3[CH:28]=[C:29]([NH:35][C:36](=[O:40])[CH2:37][CH2:38][CH3:39])[CH:30]=[CH:31][C:32]=3[O:33][CH3:34])[CH2:23][CH2:22]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1