HRID1269337

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID16756399

未命名化合物

HCID21957140

未命名化合物

PRODUCTS

生成物

结构：CC(C)C(=O)Nc1c(F)cc(F)c(C2CCN(CCCNC(=O)C(c3ccccc3)c3ccccc3)CC2)c1F

HCID18446864

未命名化合物

PROCEDURE

实验过程

Example 171 was prepared from N-(3-bromopropyl)-2,2-diphenylacetamide and 2-methyl-N-[2,4,6-trifluoro-3-(4-piperidinyl)phenyl]propanamide according to the procedures described in Scheme 14; ESMS m/e: 552.3 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1ea358cfec474f769fc6414d3f7facc3
来源数据集: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07199135B2
来源说明: uspto-grants-2007_04

反应 SMILES

Br[CH2:2][CH2:3][CH2:4][NH:5][C:6](=[O:20])[CH:7]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[CH3:21][CH:22]([CH3:41])[C:23]([NH:25][C:26]1[C:31]([F:32])=[CH:30][C:29]([F:33])=[C:28]([CH:34]2[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]2)[C:27]=1[F:40])=[O:24]>>[C:8]1([CH:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:6]([NH:5][CH2:4][CH2:3][CH2:2][N:37]2[CH2:38][CH2:39][CH:34]([C:28]3[C:27]([F:40])=[C:26]([NH:25][C:23](=[O:24])[CH:22]([CH3:21])[CH3:41])[C:31]([F:32])=[CH:30][C:29]=3[F:33])[CH2:35][CH2:36]2)=[O:20])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1