HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-methyl-N-[2,4,6-trifluoro-3-(4-piperidinyl)phenyl]propanamide → N-[3-(1-{3-[(diphenylacetyl)amino]propyl}-4-piperidinyl)-2,4,6-trifluorophenyl]-2-methylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-methyl-N-[2,4,6-trifluoro-3-(4-piperidinyl)phenyl]propanamide | HCID 16756399 | — |
| Reactant | N-(3-bromopropyl)-2,2-diphenylacetamide | HCID 21957140 | — |
| Product | N-[3-(1-{3-[(diphenylacetyl)amino]propyl}-4-piperidinyl)-2,4,6-trifluorophenyl]-2-methylpropanamide | HCID 18446864 | — |
Reaction Steps
Example 171 was prepared from N-(3-bromopropyl)-2,2-diphenylacetamide and 2-methyl-N-[2,4,6-trifluoro-3-(4-piperidinyl)phenyl]propanamide according to the procedures described in Scheme 14; ESMS m/e: 552.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07199135B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-1ea358cfec474f769fc6414d3f7facc3 |
| Source note | uspto-grants-2007_04 |