HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-methyl-N-[2,4,6-trifluoro-3-(4-piperidinyl)phenyl]propanamide → N-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-2,4,6-trifluorophenyl}-2-methylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-methyl-N-[2,4,6-trifluoro-3-(4-piperidinyl)phenyl]propanamide | HCID 16756399 | — |
| Reactant | N-(3-bromopropyl)-2,2-bis(4-fluorophenyl)acetamide | HCID 18446872 | — |
| Product | N-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-2,4,6-trifluorophenyl}-2-methylpropanamide | HCID 16756074 | — |
Reaction Steps
Example 173 was prepared from N-(3-bromopropyl)-2,2-bis(4-fluoro phenyl)acetamide and 2-methyl-N-[2,4,6-trifluoro-3-(4-piperidinyl)phenyl]propanamide according to the procedures described in Scheme 14; ESMS m/e: 588.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07199135B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-ff847f46aafa4831846695124a87f899 |
| Source note | uspto-grants-2007_04 |