Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1269454Generated: November 3, 2026

Trifluoroacetic acid → HCID 18448579, compound

https://huagongshe.com/reaction/1269454

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 69427203HCID 69427203—
SolventDichloromethaneHCID 6344—
ProductHCID 18448579HCID 18448579—

Reaction Steps

4-Benzyloxy-2-[(6-hydroxymethyl-1,2,3,4-tetrahydro-naphthalen-1-ylcarbamoyl)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester (480 mg. 97 mmol) was dissolved in 25 mL CH2Cl2 and treated with 10 mL TFA and stirred at RT for 15 min, then concentrated to afford the title compound as a colorless glass. (MS,395, M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07199244B2
Source datasetuspto-grants-2007_04
ORD IDord-6ec1d6ce194d496eb6224180ac0d66ca
Source noteuspto-grants-2007_04