HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propylamine → Ethyl {2-methyl-4-[(propylamino)methyl]phenoxy}acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propylamine | HCID 7852 | — |
| Reactant | Ethyl {4-[(butylamino)methyl]-2-methylphenoxy}acetate | HCID 58622846 | — |
| Product | Ethyl {2-methyl-4-[(propylamino)methyl]phenoxy}acetate | HCID 58622861 | — |
Reaction Steps
Prepared using n-propyl amine (1.67 mL, 20.3 mmol) and the synthetic procedure described for Intermediate 7. Purification of the crude product by SCX SPE (5×10 g) loading and washing with EtOH and then eluting product with 5% NH3 in EtOH, and removal of the solvent in vacuo yielded the title compound as a brown oil (2.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07199239B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-2a2f87f217ca4b87bae89dabd9c6c931 |
| Source note | uspto-grants-2007_04 |