HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propanal → N-Propyl-N-[4'-(trifluoromethyl)-1,1'-biphenyl-3-yl]amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propanal | HCID 527 | — |
| Reactant | N-Pentyl-N-[4'-(trifluoromethyl)-1,1'-biphenyl-3-yl]amine | HCID 18448425 | — |
| Product | N-Propyl-N-[4'-(trifluoromethyl)-1,1'-biphenyl-3-yl]amine | HCID 18448426 | — |
Reaction Steps
Prepared using propionaldehyde (91 μl, 1.26 mmol) and the synthetic procedure described for Intermediate 19. Purification by Biotage™ chromatography (40 g Silica column), eluted with 1:50 EtOAc:cyclohexane afforded the title compound as a white crystalline solid (0.22 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07199239B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-15f86a42885e42a59ff4e496d5d6550c |
| Source note | uspto-grants-2007_04 |