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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1269645Generated: October 31, 2026

Tolylboronic acid → 4-Chloro-5-methyl-6-(4-methylphenyl)pyrimidine

https://huagongshe.com/reaction/1269645

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolylboronic acidHCID 79799—
Reactant4,6-Dichloro-5-methylpyrimidineHCID 818860—
Reactant4-chloro-5-methyl-6-[4-(trifluoromethyl)phenyl]PyrimidineHCID 18448403—
Product4-Chloro-5-methyl-6-(4-methylphenyl)pyrimidineHCID 18448402—

Reaction Steps

Prepared from 4-methylphenylboronic acid and and 4,6-dichloro-5-methylpyrimidine using the procedure described for Intermediate 62.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07199239B2
Source datasetuspto-grants-2007_04
ORD IDord-4a1a5a8a7921476ca1bfcc2c4b66e8e9
Source noteuspto-grants-2007_04