HCID 9836178, compound → HCID 9908775, compound

Participants

Reaction Steps

To a solution of N-(1-benzyl-4-piperidinyl)-1H-indazol-5-amine (3.06 g, 10.0 mmol) in tetrahydrofuran (31 ml) was added a 1N-hydrochloric acid/ether solution (25 ml) at room temperature, and stirred at room temperature for 30 minutes. The solid precipitated was collected by filtration and recrystallized from methanol to obtain N-(1-benzyl-4-piperidinyl)-1H-indazol-5-amine dihydrochloride monohydrate (2.86 g, 72%).

Provenance & Evidence