Hydrochloric Acid → HCID 20571397, compound

HRID 126981Notes

Reaction equation

HRID 126981 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:16]([CH3:18])[CH3:17])[C:14]#[N:15].Cl.[CH3:20][OH:21]>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:16]([CH3:18])[CH3:17])[C:14](=[NH:15])[O:21][CH3:20]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 20283993HCID 20283993, compound

Product 1

HCID 20571397HCID 20571397, compound

Procedure

Following the procedure described in Example 6, 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutyronitrile is reacted with methanol and hydrogen chloride to give methyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanimidate, which is then reacted with 3-phenoxybenzyl alcohol, yielding the desired compound 3-phenoxybenzyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanimidate.

Sources & evidence

ORD record
ord-fe4a7e83238d48d487a5a33d1665a188
Source dataset
uspto-grants-1981_03
Patent number
US04254264

Reaction notes

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