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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1269929Generated: October 31, 2026

4-(ethylthio)-1H-indazol-5-ol → 2-(cis-3-{[4-(ethylthio)-1H-indazol-5-yl]oxy}cyclohexyl)-1H-isoindole-1,3(2H)-dione

https://huagongshe.com/reaction/1269929

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(ethylthio)-1H-indazol-5-olHCID 22933903—
Reactanttrans-2-(3-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dioneHCID 60011725—
ReactantHCID 178477322HCID 178477322—
Product2-(cis-3-{[4-(ethylthio)-1H-indazol-5-yl]oxy}cyclohexyl)-1H-isoindole-1,3(2H)-dioneHCID 69432528—

Reaction Steps

The title compound was synthesized by carrying out reaction according to the method described in Example 610, except for using the trans-2-(3-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione obtained in Example 385, (b) and the 4-(ethylthio)-1H-indazol-5-ol obtained in Example 628, as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07199147B2
Source datasetuspto-grants-2007_04
ORD IDord-ed2a4448d7b843d78083e82e0058b660
Source noteuspto-grants-2007_04