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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1269931Generated: November 1, 2026

4-(ethylthio)-1H-indazol-5-ol → 2-(trans-3-{[4-(ethylthio)-1H-indazol-5-yl]oxy}cyclohexyl)-1H-isoindole-1,3(2H)-dione

https://huagongshe.com/reaction/1269931

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(ethylthio)-1H-indazol-5-olHCID 22933903—
Reactant(1S,3R)-2-(3-hydroxy-cyclohexyl)-isoindole-1,3-dioneHCID 69434411—
Product2-(trans-3-{[4-(ethylthio)-1H-indazol-5-yl]oxy}cyclohexyl)-1H-isoindole-1,3(2H)-dioneHCID 69431070—

Reaction Steps

The title compound was synthesized by carrying out reaction according to the method described in Example 610, except for using the cis-2-(3-hydroxycyclohexyl)-1H-isoindole-1,3(2H)-dione obtained in Example 326, (d) and the 4-(ethylthio)-1H-indazol-5-ol obtained in Example 628, as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07199147B2
Source datasetuspto-grants-2007_04
ORD IDord-ae0e87f7510a4fdcb086d5d65e2053ff
Source noteuspto-grants-2007_04