反应详情

A solution of intermediate 12 (100 mg) in 10% TFA/DCM (1 mL) was stirred at room temperature for 2 h. The solvent was partially evaporated under reduced pressure. For five times the residual was diluted in DCM (2 mL) and concentrated under reduced pressure. Final solvent evaporation afforded the title compound (103.4 mg).

1. customThe solvent was partially evaporated under reduced pressure
2. additionFor five times the residual was diluted in DCM (2 mL)
3. concentrationconcentrated under reduced pressure
4. customFinal solvent evaporation