HCID 18449248, compound → HCID 18449204, compound

Participants

Reaction Conditions

Reaction Steps

A solution of isopropyl-[1-methoxy-7-(4-methyl-piperazin-1-ylmethyl)-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]amine (12 mg) in AcOH (1 mL) and 48% HBr (0.5 mL) was stirred at 23° C. for 90 min., then was heated to 90° C. for 100 min. After cooling to 23° C., the solution was concentrated. The resulting residue was concentrated from toluene. Trituration of the residue with MeOH/EtOAc afforded the title compound as a light yellow solid. MS (M+H)+=356.4.

Provenance & Evidence