Hydrochloric Acid → HCID 20288856, compound

HRID 127024Notes

Reaction equation

HRID 127024 reaction equation
[ClH:1].[NH2:2][C:3]1[N:8]=[C:7]([NH2:9])[C:6]([CH2:10][C:11]2[CH:16]=[C:15]([O:17][CH3:18])[C:14]([C:19]([CH3:21])=[CH2:20])=[C:13]([O:22][CH3:23])[CH:12]=2)=[CH:5][N:4]=1>CO>[ClH:1].[NH2:2][C:3]1[N:8]=[C:7]([NH2:9])[C:6]([CH2:10][C:11]2[CH:12]=[C:13]([O:22][CH3:23])[C:14]([C:19]([CH3:21])=[CH2:20])=[C:15]([O:17][CH3:18])[CH:16]=2)=[CH:5][N:4]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 479082HCID 479082, compound

Product 1

HCID 20288856HCID 20288856, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3.3 Ml. of 1-N hydrochloric acid were added to a solution of 0.9 g. of 2,4-diamino-5-(4-isopropenyl-3,5-dimethoxybenzyl)-pyrimidine in 100 ml. of methanol. The solution was concentrated to 25 ml. and, after cooling, the crystals were removed by filtration under suction and dried. The resulting 2,4-diamino-5-(4-isopropenyl-3,5-dimethoxybenzyl)-pyrimidine hydrochloride melts at above 300° C.

Workup

  1. concentrationThe solution was concentrated to 25 ml
  2. temperatureand, after cooling
  3. customthe crystals were removed by filtration under suction
  4. customdried

Sources & evidence

ORD record
ord-c12882acb40444e8871bbc52806878d9
Source dataset
uspto-grants-1981_03
Patent number
US04254286

Reaction notes

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