Ammonia → HCID 22329612, compound

Participants

Reaction Steps

4-Bromobenzonitrile (36.4 g, 0.2 mol), ammonium bromide (39.2 g, 0.4 mol) and ammonia gas (34.0 g, 2 mol) are heated under autogenous pressure in an autoclave for 9 h at 140–150° C. The autoclave contents are concentrated and extracted by stirring with ethanol. The residue is filtered off and again extracted by stirring with ethanol. The extracts are combined and concentrated to about 100 ml. The precipitated solid is filtered off with suction, washed with ethanol and dried.

Provenance & Evidence