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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 127047Generated: October 31, 2026

Citric Acid → HCID 178518214, compound

https://huagongshe.com/reaction/127047

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCitric AcidHCID 311—
ReactantMalic AcidHCID 525—
ReactantSorbitolHCID 5780—
ReactantNeohesperidin dihydrochalconeHCID 30231—
ReactantHCID 178508931HCID 178508931—
ReactantHCID 178526002HCID 178526002—
SolventWaterHCID 962—
ProductHCID 178518214HCID 178518214—

Reaction Steps

Neohesperidin dihydrochalcone (10 g) and sorbitol (50 g) were mixed together and were heated to 140° C. to 170° C. (water or alcohol in appropriate quantities may be used to assist dissolution of the starting material). The liquified mixture was cooled to about 60° C. to 70° C., and the pH of the solution was adjusted to 5.5 to 6.0 by the addition of citric acid or malic acid. Then a mixture of disodium 5'--inosinate and disodium 5'--guanylate (0.016 g), which is commercially obtained as ribotide, was added and the entire mixture was dried by conventional methods. The dried mixture was ground into a fine powder. The resulting composition had excellent solubility in aqueous solution and gave an immediate sweet taste with no methanol-like aftertaste. This composition may be used to sweeten beverages and other food products.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04254155
Source datasetuspto-grants-1981_03
ORD IDord-ce44b1806a0949bbbe4a6081be05a341
Source noteuspto-grants-1981_03