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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1270705Generated: October 31, 2026

3,5-Dimethylphenol → 4-(3,5-Dimethylphenoxy)benzonitrile

https://huagongshe.com/reaction/1270705

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DimethylphenolHCID 7948—
ReactantIodobenzeneHCID 11575—
Reactant4-IodobenzonitrileHCID 76467—
Product4-(3,5-Dimethylphenoxy)benzonitrileHCID 10263009—

Reaction Steps

Example 3.1 was repeated, replacing the phenol with 244 mg of 3,5-dimethylphenol (2 mmoles) and the iodobenzene with 595 mg of 4-iodobenzonitrile (2.6 mmoles), the latter being added at the same time as the 3,5-dimethylphenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07202367B2
Source datasetuspto-grants-2007_04
ORD IDord-db3f3eabfcc745e1bb9463af2232e0da
Source noteuspto-grants-2007_04