HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-aminobenzoate → HCID 18452518, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-aminobenzoate | HCID 12082 | — |
| Reactant | HCID 59556245 | HCID 59556245 | — |
| Product | HCID 18452518 | HCID 18452518 | 71.2% |
Reaction Steps
Analogous to the method described in Example 1, 2-(chlorocarbonyl)-4,5-difluorophenyl acetate (0.2 g, 0.85 mmol) and methyl 4-aminobenzoate (0.174 g, 1.1 mmol) were coupled to yield methyl 4-(4,5-difluoro-2-hydroxybenzamido)benzoate (0.186 g, 64%). RP-HPLC: 2.61 min; ES-MS (M+H)+=308.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07205296B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-4cfeabd2623544e1a084825fbe7a9358 |
| Source note | uspto-grants-2007_04 |