Acetone → 4-(Isopropylamino)butanol

HRID 1271234노트

반응식

HRID 1271234 반응식
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][OH:6].[CH3:7][C:8]([CH3:10])=O>C(O)C.[Pt](=O)=O>[CH:8]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][OH:6])([CH3:10])[CH3:7]

참가 물질

5

반응물 2

HCID 180AcetoneHCID 258684-Amino-1-butanol

생성물 1

HCID 129509864-(Isopropylamino)butanol

시약·촉매·용매 2

HCID 345198Adams' catalyst촉매HCID 702Ethanol용매

실험 절차

100.40 g of 4-amino-1-butanol was dissolved in a mixed solvent of 108 ml of acetone and 160 ml of ethanol and, after adding 2.1 g of platinum (IV) oxide, hydrogenation was carried out under the pressure of 2 to 3 atms for 48 hours. A catalyst was removed by filtering the reaction solution and the filtrated was concentrated to obtain 147.64 g of the desired compound as a colorless oily substance.

후처리

  1. customA catalyst was removed
  2. filtrationby filtering the reaction solution
  3. concentrationthe filtrated was concentrated

출처 및 근거

ORD 기록
ord-d84ac96ce73e42c589df5a021eb8f80a
출처 데이터셋
uspto-grants-2007_04
특허 번호
US07205302B2

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