5-Chloro-2,3-Diphenylpyrazine → 1-{[N-(5,6-diphenylpyrazin-2-yl)-N-methylamino]methyl}-3-(methoxymethoxy)benzene

Participants

Reaction Steps

In the same manner as in the step 1 of Example 9, except that 2-chloro-5,6-diphenylpyrazine was used in place of 2-chloro-5,6-di-p-tolylpyrazine and 3-(methoxymethoxy)-N-methylbenzylamine was used in place of 4-(methylamino)-1-butanol, the desired compound was prepared as a colorless crystal having a melting point of 109 to 111° C.

Provenance & Evidence