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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1271291Generated: November 1, 2026

2,3-Diphenyl-5-(methylamino)pyrazine 1-oxide → 2,3-diphenyl-5-{N-[4-(tert-butoxycarbonylmethoxy)butyl]-N-methylamino}pyrazine 1-oxide

https://huagongshe.com/reaction/1271291

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Diphenyl-5-(methylamino)pyrazine 1-oxideHCID 22932010—
ReactantTert-butyl (4-bromobutyloxy)acetateHCID 86592459—
Product2,3-diphenyl-5-{N-[4-(tert-butoxycarbonylmethoxy)butyl]-N-methylamino}pyrazine 1-oxideHCID 22931984—

Reaction Steps

In the same manner as in Example 22, except that 2,3-diphenyl-5-(methylamino)pyrazine 1-oxide was used in place of 5,6-diphenyl-2-(methylamino)pyrazine and 2-(4-bromobutyloxy)acetic acid tert-butyl ester was used in place of 2-(4-bromobutyloxy)acetic acid methyl ester, the desired compound was prepared as a pale yellow oily substance.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07205302B2
Source datasetuspto-grants-2007_04
ORD IDord-6f65e69dfaf445298e4979cdcbd0bc42
Source noteuspto-grants-2007_04