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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1271293Generated: November 2, 2026

4,5-Di-p-tolyl-2-(methylamino)pyrimidine → 2-{4-[N-(4,5-di-p-tolylpyrimidin-2-yl)-N-methylamino]butyloxy}acetic Acid Tert-Butyl Ester

https://huagongshe.com/reaction/1271293

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,5-Di-p-tolyl-2-(methylamino)pyrimidineHCID 22931959—
ReactantTert-butyl (4-bromobutyloxy)acetateHCID 86592459—
Product2-{4-[N-(4,5-di-p-tolylpyrimidin-2-yl)-N-methylamino]butyloxy}acetic Acid Tert-Butyl EsterHCID 69355321—

Reaction Steps

In the same manner as in Example 22, except that 4,5-di-p-tolyl-2-(methylamino)pyrimidine was used in place of 5,6-diphenyl-2-(methylamino)pyrazine and 2-(4-bromobutyloxy)acetic acid tert-butyl ester was used in place of 2-(4-bromobutyloxy)acetic acid methyl ester, the desired compound was prepared as a pale yellow oily substance.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07205302B2
Source datasetuspto-grants-2007_04
ORD IDord-f2b89caa543e49e9862bb469ba76c4f0
Source noteuspto-grants-2007_04