Methylamine → HCID 54005524, compound

HRID 127132Notes

Reaction equation

HRID 127132 reaction equation
Br[CH2:2][CH:3]1[O:7][CH:6]([CH3:8])[CH:5]([CH3:9])[O:4]1.[CH3:10][NH2:11]>>[CH3:9][CH:5]1[CH:6]([CH3:8])[O:7][CH:3]([CH2:2][NH:11][CH3:10])[O:4]1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 128944572-Bromomethyl-4,5-dimethyl-1,3-dioxolane

Product 1

HCID 54005524HCID 54005524, compound

Procedure

2-Bromomethyl-4,5-dimethyl-1,3-dioxolane (100 grams) and 40% aqueous methylamine (300 ml) were charged into a glass reaction vessel fitted with a mechanical stirrer and thermometer and were stirred at room temperature for a period of about 14 hours. The reaction mixture was then extracted with diethyl ether. The extract was dried and the ether stripped off using a rotary evaporator to yield the desired product N-(4,5-dimethyl-1,3-dioxolan-2-ylmethyl)methylamine as the residue.

Workup

  1. customfitted with a mechanical stirrer
  2. extractionThe reaction mixture was then extracted with diethyl ether
  3. customThe extract was dried
  4. customa rotary evaporator

Sources & evidence

ORD record
ord-d0e6e84784a14506a8ac47b5903bab33
Source dataset
uspto-grants-1981_03
Patent number
US04255182

Reaction notes

Loading…