HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 18453527, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 1-[2-(4-nitro-benzyloxy)-ethyl]-1H-[1,2,3]triazole | HCID 18453517 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 18453527 | HCID 18453527 | 95% |
Reaction Steps
1-[2-(4-Nitro-benzyloxy)-ethyl]-1H-[1,2,3]triazole (3.6 g, 14.5 mmol) and platinum dioxide (0.4 g) were suspended in methanol (30 ml) and THF (30 ml) and hydrogenated for 3 h at 42 mbar. After filtration and concentration 3 g (95%) 4-(2-[1,2,3]triazol-1-yl-ethoxymethyl)-phenylamine were obtained as beige solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07205326B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-299de1515b28463fa6e3ba83b5ad3a36 |
| Source note | uspto-grants-2007_04 |