Hydrochloric Acid → HCID 68829855, compound

Participants

Reaction Steps

To a stirred solution of Example 42 (250 mg, 0.80 mmol) in EtOAc (3 ml) was added a saturated solution of dry HCl in EtOAc (2 ml). This solution was stirred at RT for 30 min to result a white precipitate. The product was collected by filtration and dried under vacuum to give 279 mg of the product as a white solid; 1H NMR (D2O, 300 MHz) δ 1.41–1.62 (m, 2H), 1.75–1.87 (m, 2H), 2.02–2.17 (m, 2H), 2.27–2.74 (m, 4H), 3.67–4.20 (m, 4H), 4.41 (d, J=6.9 Hz, 2H), 5.00–5.15 (m, 1H), 5.43–5.60 (m, 1H), 8.52 (s, 1H), 9.27 (s, 1H).

Provenance & Evidence