Hydrochloric Acid → HCID 68588465, compound

HRID 1271520Notes

Reaction equation

HRID 1271520 reaction equation
C(OC([N:8]1[C@H:17]([C:18]([OH:20])=[O:19])[CH2:16][C@@H:15]2[C@@H:10]([CH2:11][CH2:12][C@H:13]([O:21][C:22]3[CH:27]=[C:26]([N:28]4[CH:32]=[CH:31][CH:30]=[N:29]4)[CH:25]=[CH:24][C:23]=3[C:33]3[N:34]=[N:35][NH:36][N:37]=3)[CH2:14]2)[CH2:9]1)=O)(C)(C)C.[ClH:38]>C(Cl)Cl.C(OCC)C>[ClH:38].[N:28]1([C:26]2[CH:25]=[CH:24][C:23]([C:33]3[N:37]=[N:36][NH:35][N:34]=3)=[C:22]([CH:27]=2)[O:21][C@H:13]2[CH2:12][CH2:11][C@@H:10]3[C@@H:15]([CH2:16][C@@H:17]([C:18]([OH:20])=[O:19])[NH:8][CH2:9]3)[CH2:14]2)[CH:32]=[CH:31][CH:30]=[N:29]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 68587833HCID 68587833, compound

Product 1

HCID 68588465HCID 68588465, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent

Procedure

To 0.040 g of the material from Step C, above, dissolved in 5 mL CH2Cl2, is added 3 mL 2M HCl in diethyl ether. After stirring four hours at ambient temperature, the reaction is concentrated in vacuo.

Workup

  1. concentrationthe reaction is concentrated in vacuo

Sources & evidence

ORD record
ord-26b40c33f0b748a0bbec43797fabb842
Source dataset
uspto-grants-2007_04
Patent number
US07205313B2

Reaction notes

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