反应详情

Methyl 3,5-bis(dimethylcarbamoylthio)benzoate (34.2 g, 0.100 mol) was made to react with a mixture of 43 g of 28% methanol solution of sodium methoxide (0.223 mol) and methanol (150 ml) at 22–25° C. After addition of 500 ml of ice-water, the reaction mixture was neutralized with concentrated hydrochloric acid to give a colorless crystals. The crystals thus obtained were purified by means of recrystallization from methanol giving 12.5 g (62.5%) of methyl 3,5-dimercaptobenzoate as a colorless powder. The melting point is 61–62° C.

1. customto give a colorless crystals
2. customThe crystals thus obtained
3. customwere purified by means of recrystallization from methanol giving 12.5 g (62.5%) of methyl 3,5-dimercaptobenzoate as a colorless powder