反应详情

Carbonyl diimidazole (7.6 g) was added to a solution of 2-amino-4-fluorophenol (5 g, 39 mmol) in dichloromethane (0.100 ml). After 14 hours the solution was washed with 5M aqueous HCl, water, and dried over magnesium sulfate. The solution was filtered through a plug of silica and evaporated affording a white solid (4.0 g, 66%).

1. washAfter 14 hours the solution was washed with 5M aqueous HCl, water
2. dry with materialdried over magnesium sulfate
3. filtrationThe solution was filtered through a plug of silica
4. customevaporated