3-(2,6dichloro-4-(benzyloxy)phenoxy)-1-propyl alcohol → HCID 18454988, compound

Participants

Reaction Steps

This compound was prepared in a manner analogous to that of Step B of Example 1, by the treatment of 11.8 grams (0.036 mole) of 3-[2,6-dichloro-4-(phenylmethoxy)phenoxy]propan-1-ol with hydrogen gas in the presence of a catalytic amount of 10% palladium on carbon in ethanol using a Parr hydrogenation apparatus. Following the theoretical uptake of hydrogen, the reaction mixture was and filtered and concentrated under reduced pressure to a residue, yielding 8.0 grams of the subject compound.

Provenance & Evidence