Sodium hydride → 2-BroMostyrene oxide

HRID 127184Notes

Reaction equation

[H-].[Na+].[I-].[CH3:4][S+](C)C.[Br:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=[O:12]>>[Br:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]1[O:12][CH2:4]1

Participants

Reactant 3

HCID 24758Sodium hydride

HCID 75127Trimethylsulfonium iodide

HCID 811292-Bromobenzaldehyde

Product 1

HCID 110308142-BroMostyrene oxide

Procedure

Following the procedure of Example 7 and employing 42.0 g of 57% of sodium hydride in mineral oil, 200 g (0.1 mol) of trimethylsulfonium iodide and 70.4 g (0.50 mol) of o-bromo-benzaldehyde there is obtained o-bromostyrene oxide.

Sources & evidence

ORD record: ord-444117b4d8be4a3f8fcc0e7b00bf1a4a
Source dataset: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04255422

Reaction notes

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