Trifluoroacetic acid → HCID 9982011, compound

Participants

Reaction Steps

N-(2-Amino-2-methyl-propyl)—N-[1-(3-benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-2-methyl propyl]-acrylamide: According to the procedure of Example 1d above, ({acryloyl-[1-(3-benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-2-methyl-propyl]-amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester (730 mg, 1.29 mmol) was treated with 50% TFA in CH2Cl2 (10 mL) to give the title compound: MS (ES) m/e 467.2 (M+H)+.

Provenance & Evidence