HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-(2-oxoethyl)carbamate → HCID 10457279, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-(2-oxoethyl)carbamate | HCID 4247255 | — |
| Reactant | HCID 18455022 | HCID 18455022 | — |
| Reactant | 2-(1-amino-2-methylpropyl)-3-benzyl-7-chloroquinazolin-4(3H)-one | HCID 22238798 | — |
| Reactant | Sodiumacetoxyborohydride | HCID 23670382 | — |
| Product | HCID 10457279 | HCID 10457279 | — |
Reaction Steps
Preparation of {2-[1-(3-benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-2-methyl-propylamino]-ethyl}-carbamic acid tert-butyl ester: Following the procedure of Example 1b, 2-(1-amino-2-methyl-propyl)-3-benzyl-7-chloro-3H-quinazolin-4-one, (2-oxo-ethyl)-carbamic tert-butyl ester and sodium acetoxyborohydride gave the title compound as a white solid: MS (ES) m/e 485.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07208487B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-6fbdb1973f204f9394df66f294b06d42 |
| Source note | uspto-grants-2007_04 |