Methylamine → HCID 18456582, compound

HRID 1272053Notes

Reaction equation

HRID 1272053 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=O)[CH:5]=[CH:6][C:7]=1[OH:8].[CH3:13][NH2:14]>>[F:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([NH:14][CH3:13])=[O:12])[CH:5]=[CH:6][C:7]=1[OH:8]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 680143-Fluoro-4-hydroxybenzeneacetic acid

Product 1

HCID 18456582HCID 18456582, compound

Procedure

was prepared from 3-fluoro-4-hydroxyphenylactic acid and methyl amine following Method A. S1H NMR (300 MHz, CD3OD) δ 7.89 (s, 1H), 6.90 (d, 1H, J=13.37 Hz), 6.82–6.71 (m, 1H), 3.29 (s, 2H), 2.62 (s, 3H). LCMS (ESI+) [M+H]/z Calc'd 184, found 184.

Sources & evidence

ORD record
ord-e6448182ba5f407ebca87e9d0bda3226
Source dataset
uspto-grants-2007_04
Patent number
US07208500B2

Reaction notes

Loading…