反应详情

(E)-2-Thiophen-2-yl-ethenesulfonic acid (1,1,3,3-tetramethyl-butyl)-amide (5.17 g, 17.2 mmol) was stirred for 15 minutes in a 1:1 mixture of trifluoroacetic acid and dichloromethane (40 mL). The mixture was concentrated in vacuo to afford a solid that was washed with dichloromethane (10 mL) in heptane (100 mL). The resultant solid was collected by suction filtration and dried under vacuum at ambient temperature to afford (E)-2-thiophen-2-yl-ethenesulfonic acid amide (2.89 g, 89%).

1. concentrationThe mixture was concentrated in vacuo
2. customto afford a solid
3. washthat was washed with dichloromethane (10 mL) in heptane (100 mL)
4. filtrationThe resultant solid was collected by suction filtration
5. customdried under vacuum at ambient temperature