Trifluoroacetic acid → HCID 86596345, compound

Participants

Reaction Steps

To a solution of 0.20 g (0.59 mmol) (4R,9aR)-6-chloro-4,7-dimethyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester in 2 mL dichloromethane was added 0.91 mL (1.35 g, 11.8 mmol) trifluoroacetic acid. After 30 min., all volatile components were removed at a rotary evaporator and the residue was purified by column chromatography on silica gel with dichloromethane:methanol:ammonia (19:1:0.1) as eluant to give the desired compound as a colourless oil (95.9%).

Provenance & Evidence