Methyl Isocyanate → HCID 86737558, compound

HRID 127216Notes

Reaction equation

[N:1](=[C:3]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5]([CH3:15])([CH3:14])[S:4]1)[OH:2].[CH3:16][N:17]=[C:18]=[O:19]>>[CH3:16][NH:17][C:18]([O:2][N:1]=[C:3]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5]([CH3:15])([CH3:14])[S:4]1)=[O:19]

Participants

Reactant 2

HCID 12228Methyl Isocyanate

HCID 86737559HCID 86737559, compound

Product 1

HCID 86737558HCID 86737558, compound

Procedure

2-oxo-4-phenyl-5,5-dimethyl-3-thiazoline-oxime was reacted with methyl isocyanate as described in Example 4 to yield 2-oxo-4-phenyl-5,5-dimethyl-3-thiazoline-O-(methylcarbamoyl)-oxime, m.p. 135°-137° C. The 2-oxo-4-phenyl-5,5-dimethyl-3-thiazoline-oxime starting material (m.p. 147°-149° C.) was prepared from 2-methyl-1-phenyl-2-thiocyanato-1-propanone (b.p. [0.02 mm] 98°-100° C.).

Sources & evidence

ORD record: ord-1f3ba63b95b84c138eed808cc6f243c5
Source dataset: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04255436

Reaction notes

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