HCID 69357759, compound → HCID 69359065, compound

Participants

Reaction Steps

A solution of 0.138 g (4R,9aR)-7-fluoro-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester in 1.5 mL trifluoroacetic acid was kept at room temperature for 1 h. The solvent was evaporated and the residue was purified by chromatography on silica gel with dichloromethane:methanol:sat. ammonia (9:1:0.1) to yield 0.070 g (4R,9aR)-7-fluoro-4-methyl-1,2,3,4,9,9a-hexahydro-2,4a,5-triaza-fluorene as slightly yellow oil.

Provenance & Evidence