HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Methoxyphenyl)-5-(4-(4-methoxyphenyl)piperazin-1-yl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol → 4-(4-Methoxyphenyl)-1-(3-(4-methoxyphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Methoxyphenyl)-5-(4-(4-methoxyphenyl)piperazin-1-yl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol | HCID 58847352 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(4-Methoxyphenyl)-1-(3-(4-methoxyphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine | HCID 18456073 | 88% |
Reaction Steps
Using 3-(4-methoxyphenyl)-5-(4-(4-methoxyphenyl)piperazin-1-yl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol obtained in Example 66, the title compound was synthesized in the same manner as in Example 46. Yield 88%. mp. 205–207° C. (ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07208495B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-83fa6f00ddba4885b19ddbc3e15ddf7f |
| Source note | uspto-grants-2007_04 |