HRID1272327

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(C2(O)c3c(C)c(N4CCC(c5ccc(OC)c(OC)c5)CC4)c(C)c(C)c3OC2(C)C)cc1

HCID58847335

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C2c3c(C)c(N4CCC(c5ccc(OC)c(OC)c5)CC4)c(C)c(C)c3OC2(C)C)cc1

HCID18456027

未命名化合物

收率 82%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID21896459

未命名化合物

PROCEDURE

实验过程

Using 3-(4-methoxyphenyl)-5-(4-(3,4-dimethoxyphenyl)piperidino)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol obtained in Example 85, the title compound was synthesized in the same manner as in Example 46. Yield 82%. mp. 154–156° C. (hexane-methanol).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-08769d1daaf9472e9b19398707dbd609
来源数据集: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07208495B2
来源说明: uspto-grants-2007_04

反应 SMILES

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2(O)[C:13]3[C:14]([CH3:36])=[C:15]([N:20]4[CH2:25][CH2:24][CH:23]([C:26]5[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[C:28]([O:34][CH3:35])[CH:27]=5)[CH2:22][CH2:21]4)[C:16]([CH3:19])=[C:17]([CH3:18])[C:12]=3[O:11][C:10]2([CH3:38])[CH3:37])=[CH:5][CH:4]=1>CCCCCC.CO>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[C:13]3[C:14]([CH3:36])=[C:15]([N:20]4[CH2:25][CH2:24][CH:23]([C:26]5[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[C:28]([O:34][CH3:35])[CH:27]=5)[CH2:22][CH2:21]4)[C:16]([CH3:19])=[C:17]([CH3:18])[C:12]=3[O:11][C:10]2([CH3:38])[CH3:37])=[CH:5][CH:4]=1