HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Methoxyphenyl)-5-(4-(3,4-dimethoxyphenyl)piperidino)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol → 1-(3-(4-Methoxyphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-4-(3,4-dimethoxyphenyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Methoxyphenyl)-5-(4-(3,4-dimethoxyphenyl)piperidino)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol | HCID 58847335 | — |
| Solvent | Hexane methanol | HCID 21896459 | — |
| Product | 1-(3-(4-Methoxyphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-4-(3,4-dimethoxyphenyl)piperidine | HCID 18456027 | 82% |
Reaction Steps
Using 3-(4-methoxyphenyl)-5-(4-(3,4-dimethoxyphenyl)piperidino)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol obtained in Example 85, the title compound was synthesized in the same manner as in Example 46. Yield 82%. mp. 154–156° C. (hexane-methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07208495B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-08769d1daaf9472e9b19398707dbd609 |
| Source note | uspto-grants-2007_04 |