Hydrochloric Acid → HCID 18456052, compound

Participants

Reaction Steps

Using pyrrolidine and 5-(4-benzyl piperazin-1-yl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol obtained in Reference Example 42, the free base was obtained in the same manner as in Example 57. The free base was treated with a 4 N hydrochloric acid in ethyl acetate solution (10 ml) to obtain the title compound. Yield 93%. mp. 224–227° C. (decomposition) (ethyl acetate-ethanol).

Provenance & Evidence